English Version
发表论文

2014年

Yue Gao, Zhan-Yi Sun, Zhi-Hua Huang, Pu-Guang Chen, Yong-Xiang Chen, Yu-Fen Zhao, and Yan-Mei Li*
“Covalent Bond or Non-Covalent Bond: a Supramolecular Strategy for the Construction of Chemically Synthesized Vaccines"
Chemistry-A European Journal

Hui Cai, Zhan-Yi Sun, Mei-Sha Chen, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
"Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells"
Angewandte Chemie- International Edition 2014, 53(6), p1699-1703 (Hot Paper)
 
2013

Hui Cai, Mei-Sha Chen, Zhan-Yi Sun, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
"Self-Adjuvanting Synthetic Antitumor Vaccines from MUC1 Glycopeptides Conjugated to T-Cell Epitopes from Tetanus Toxoid" 
Angewandte Chemie- International Edition   2013

Mei-Sha Chen, De-Sheng Zhao, Ye-Ping Yu, Wei-Wei Li, Yong-Xiang Chen, Yu-Fen Zhao, and Yan-Mei Li*
"Characterizing the Assembly Behaviors of Human Amylin: A Perspective Derived from C-terminal Variants"
Chemical Communication     2013, 49(18), p1799-1801   (Back Cover,Highlighted by ACS Noteworthy Chemistry)

Hui Cai, Zhan-Yi Sun, Zhi-Hua Huang, Lei Shi, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
“Fully Synthetic Self-Adjuvanting Thioether-Conjugated Glycopeptide-Lipopeptide Antitumor Vaccines for the Induction of Complement Dependent Cytotoxicity against Tumor Cells”
Chemistry - A European Journal   2013, 19, p1962-1970  

2012年

Jing-Wen Ma, Lei Zhao, De-Sheng Zhao, Qian Liu, Chong Liu, Wei-Hui Wu, Yong-Xiang Chen, Yu-Fen Zhao and Yan-Mei Li*
"Covalently reactive group-modified peptide that specifically reacts with lysine16 in amyloid  "
Chemical Communication     2012, 48(85), 10565-10567  

Lei Zhao, Pei Tong, Yong-Xiang Chen ,  Zhi-Wen Hu ,  Kun Wang,  Yu-Ning Zhang,  De-Sheng Zhao,  Li-Feng Cai,  Ke-Liang Liu, Yu-Fen Zhao  and Yan-Mei Li*
"A multi-functional peptide as an HIV-1 entry inhibitor based on self-concentration, recognition, and covalent attachment"
Organic & Biomolecular Chemistry  2012, 10, 6512-6520 

Zhi-Hua Huang, Lei Shi, Jing-Wen Ma, Zhan-Yi Sun, Hui Cai, Yong-Xiang Chen, Yu-Fen Zhao, and Yan-Mei Li*
"A totally synthetic, self-assembling, adjuvant-free, MUC1 glycopeptide vaccine for cancer therapy"
Journal of American Chemical Society   2012, 134(21), 8730-8733

Lan Wang#, Qian Liu#, Jin-Chun Chen, Yi-Xian Cui, Bing Zhou, Yong-Xiang Chen, Yu-Fen Zhao and Yan-Mei Li*
"Antimicrobial Activity of Human Islet Amyloid Polypeptides: An Insight into Amyloid Peptides' Connection with Antimicrobial Peptides"
Biological Chemistry   2012, 393(7), 641-646

Hui Cai, Zhi-Hua Huang, Lei Shi, Zhan-Yi Sun, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
"Variation of the Glycosylation Pattern in MUC1 Glycopeptide BSA Vaccines and its Influence on the Immune Response"  
Angewandte Chemie- International Edition  2012, 51(7), 1719-1723 
"Variation des Glycosylierungsmusters von Vakzinen aus MUC1-Glycopeptiden und Rinderserumalbumin (BSA) und der Einfluss auf die Immunreaktion"
Angewandte Chemie  2012, 124(7), 1751-1755  

Meisha Chen, Shuai Zhang, Qian Liu, Peng Liu, Katerina Busuttil, Chen Wang, Flemming Besenbacher*, Yan-Mei Li*, Mingdong Dong*
"Investigation on the annular aggregate formation of human islet amyloid polypeptide on tantalum oxide surfaces"
Chemistry - A European Journal   2012, 18( 9), 2493-2497

Ye-Ping Yu, Shuai Zhang, Qian Liu, Yan-Mei Li,* Chen Wang, Flemming Besenbacher,* and Mingdong Dong*
"2D amyloid aggregation of human islet amyloid polypeptide at the solid-liquid interface"
Soft Matter      2012, 8(5), pp1616-1622

Peng Liu, Shuai Zhang, Mei-sha Chen, Qian Liu, Chenxuan Wang, Chen Wang, Yan-Mei Li,* Flemming Besenbacher,*  Mingdong Dong*
"Co-assembly of Human Islet amyloid polypeptide (hIAPP)/Insulin"
Chemical Communication     2012, 48, pp191-193   (Front Cover)

2011

Lu Jin, Wei-Hui Wu, Qiu-Ye Li, Yu-Fen Zhao, and Yan-Mei Li*
"Copper inducing Abeta-42 rather than A 40 nanoscale oligomer formation is the key process for Abeta neurotoxicity"
Nanoscale    2011, 3, pp4746-4751

Adrian Keller*,  Monika Fritzsche, Ye-Ping Yu, Qian Liu, Yan-Mei Li, Mingdong Dong and Flemming Besenbacher
"Influence of Hydrophobicity on the Surface-Catalyzed Assembly of the Islet Amyloid Polypeptide"
ACS Nano    2011, 5(4),  pp2770-2778

Hui Cai, Zhi-Hua Huang, Lei Shi, Peng Zou, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
"Synthesis of Tn/T Antigen MUC1 Glycopeptide BSA Conjugates and their Evaluation as Vaccines"
European Journal of Organic Chemistry   2011, 3685-3689

Liu Qian, Wu Wei-hui, Fang Chuan-lin, Li Ren-wang, Lei Peng, Hu Jia, Sun Xun, Zheng Yi-zhe, Zhao Yu-fen and Yan-Mei Li*
"Mapping ApoE/A  Binding Regions to Guide Inhibitor Discovery"
Molecular BioSystems    2011, 7, pp1693-1700

Hui Cai, Zhi-Hua Huang, Lei Shi, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
"Towards a Fully Synthetic MUC 1-Based Anticancer Vaccine: Efficient Conjugation of Glycopeptides with Mono-, Di- and Tetravalent Lipopeptides by Click Chemistry"
Chemistry - A European Journal   2011, 17,  pp6396-6406

2010

Jia Hu, Ye-Ping Yu, Wei Cui, Chuan-Lin Fang, Wei-Hui Wu, Yu-Fen Zhao and Yan-Mei Li*
"Cyclen-Hybrid Compound Captures Copper to Protect INS-1 Cells from Islet Amyloid Polypeptide Cytotoxicity by Inhibiting and Lysing Effects"
Chemical Communication     2010, 46 (42), pp8023-8025

Ye-Ping Yu, Peng Le, Jia Hu, Wei-Hui Wu, Yu-Fen Zhao and Yan-Mei Li*
"Copper-induced cytotoxicity: reactive oxygen species or islet amyloid polypeptide oligomer formation"
Chemical Communication     2010, 46, pp6909-6911  (Hot Article for ChemComm)

Anton Kaiser, Nikola Gaidzik, Torsten Becker, Clara Menge, Kai Groh, Hui Cai, Yan-Mei Li, Bastian Gerlitzki, Edgar Schmitt and Horst Kunz*
"Fully Synthetic Vaccines Consisting of Tumor-Associated MUC1 Glycopeptides and a Lipopeptide Ligand of the Toll-like Receptor 2"
Angewandte Chemie- International Edition  2010, 49, pp3688-3692

2009

Wei Cui, Jing-wen Ma, Peng Lei, Wei-hui Wu, Ye-ping Yu, Yu Xiang, Ai-jun Tong, Yu-fen Zhao, Yan-Mei Li*
"Insulin is a kinetic but not a thermodynamic inhibitor of amylin aggregation"
FEBS Journal   276, 2009, p3365-3371  

Xiaojing Ma, Lei Liu, Xiaobo Mao, Lin Niu, Ke Deng, Weihui Wu, Yanmei Li, Yanlian Yang* and Chen Wang*
“Amyloid β (1–42) Folding Multiplicity and Single-Molecule Binding Behavior Studied with STM”
Journal of Molecular Biology   388, 2009, 894-901

2008年

Wu WH‡, Lei P‡, Liu Q, Hu J, Gunn A, Chen MS, Rui YF, Su XY, Xie ZP, Zhao YF, Bush A I*, Yan-Mei Li* 
“Sequestration of copper from β-amyloid promotes selective lysis by cyclen-hybrid cleavage agents”
Journal of Biological Chemistry   283(46), 2008, p31657-31664 (Highted by Nature China)

2007年

Jin-Tang Du, Chun-Hui Yu, Lian-Xiu Zhou, Wei-Hui Wu, Peng Lei, Yu-Fen Zhao, Hiroshi Nakanishi, Yan-Mei Li* 
“Phosphorylation modulates the local conformation and self-aggregation ability of a peptide from the fourth tau microtubule-binding repeat”
FEBS Journal.   274:5012-5020, 2007   

2006年

Wei-Qun Shi, Jun-Chen Dong, Yu-Fen Zhao, Yan-Mei LI*  
“Hydroxylation of 3-Nitrotyrosine and Its Derivatives by Gamma Irradiation”
Radiation Research      166,  2006,  p639–645

Yong-Xiang Chen, Jin-Tang Du, Lian-Xiu Zhou, Xiao-Hong Liu, Yu-Fen Zhao, Hiroshi Nakanishi &  Yan-Mei LI*  
“Alternative O-GlcNAcylation and O-phosphorylation of Ser16 Inducing Different Conformational Disturbance to the N-terminal Peptides of Murine Estrogen Receptor β”
Chemistry & Biology     13, 2006, p937-944

Wei-Qun Shi, Jia Hu, Wei Zhao, Hui Cai, Yu-Fen Zhao & Yan-Mei LI*  
“Identification of Radiation induced Cross-Linking between Thymine and Tryptophan by Electrospray Ionization Mass Spectrometry”
Journal of Mass Spectrometry   41, 2006, p1205-1211

Lian-Xiu Zhou, Zhi-Yang Zeng, Jin-Tang Du, Yu-Fen Zhao & Yan-Mei LI* 
“The self-assembly ability of the first microtubule-binding repeat from tau and its modulation by phosphorylation”
 Biochemical and Biophysical Research Communications   348, 2006, p637-642

Hua-Dong Liu, Yan-Mei LI*,Jin-Tang Du,Jia Hu,Yu-Fen Zhao
“Novel acetylation aided Migrating Rearrangement of Uridine-diphosphate-N-acetylglucosamine in Electrospray Ionization Multistage Tandem Mass Spectrometry”
Journal of Mass Spectrometry    41(2), 2006, p208-215

Stefanie Schlummer, Robin Vetter , Norman Kuder, Andreas Henkel, Yong-Xiang Chen, Yan-Mei LI, Jürgen Kuhlmann*, Herbert Waldmann*
“Influence of Serine O-Glycosylation or O-Phoshorylation Close to the vJun Nuclear Localisation Sequence on Nuclear Import”
ChemBioChem   7(1), 2006, p88-97

2005年

Ni F, Li W, Yan-Mei LI, Zhao YF*
“Analysis of the phosphoryl transfer mechanism of c-AMP dependent protein kinase (PKA) by penta-coodinate phosphoric transition state theory”
Current Protein & Peptide Science  6 (5), Oct 2005, p437-442

Jin-Tang Du, Yan-Mei LI*, Wei Wei, Guo-Shi Wu, Yu-Fen Zhao, Kenji Kanazawa, Tadashi Nemoto, Hiroshi Nakanishi
“Low Barrier Hydrogen Bond Between Phosphate and Amide Group in Phosphopeptide”
Journal of the American Chemical Society   127,  2005,  p16350-16351

2004年

S.Z.Luo, Yan-Mei LI*, W.Qiang, Y.F.Zhao, H.Abe, T.Nemoto, X.R.Qin & H.Nakanishi 
“Detection of Specific Non-Covalent Interaction of Peptide With DNA by MALDI-TOF”
Journal of the American Society for Mass Spectrometry   15(1), 2004(Jan), p28-31

2003年

Z.Z.Chen, B.Tan, Yan-Mei LI, Y.F.Zhao, Y.F. Tong & J.F. Wang
“Activity Difference between alpha-COOH and beta-COOH in N-Phosphoryl Aspartic Acids”
Journal of Organic Chemistry     68, 2003, p4052-4058