(1) Shengnan Zhang#, Yu-Qing Liu#, Chunyu Jia#, Yeh-Jun Lim#, Guoqin Feng#, Enquan Xu, Houfang Long, Yasuyoshi Kimura, Youqi Tao, Chunyu Zhao, Chuchu Wang, Zhenying Liu, Jin-Jian Hu, Meng-Rong Ma, Zhijun Liu, Lin Jiang, Dan Li, Renxiao Wang, Valina L. Dawson, Ted M. Dawson*, Yan-Mei Li*, Xiaobo Mao*, Cong Liu*
“Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease”
Proc Natl Acad Sci USA, 2021, 118 (26), e2011196118;
DOI: 10.1073/pnas.2011196118

(2) Chu-Qiao Liang and Yan-Mei Li*
“Peptides for disrupting and degrading amyloids”
Current Opinion in Chemical Biology, 2021, 64:124-130
DOI: 10.1016/j.cbpa.2021.05.011

(3) Wen-Hao Li, Jun-Jun Wu, Lie Wu, Bo-Dou Zhang, Hong-Guo Hu, Lang Zhao, Zhi-Bin Li, Xue-Feng Yu*, Yan-Mei Li*
“Black Phosphorous Nanosheet: A Novel Immune-Potentiating Nanoadjuvant for Near-Infrared-Improved Immunotherapy”
Biomaterials, 2021, 273:120788
DOI: 10.1016/j.biomaterials.2021.120788

(4) Wen-Hao Li, Yan-Mei Li*
“Chemical Strategies to Boost Cancer Vaccines”
Chemical Reviews, 2020, 120(20), 11420-11478
DOI: 10.1021/acs.chemrev.9b00833

(5) Kun Zhao#, Yeh-Jun Lim#, Zhenying Liu#, Houfang Long, Yunpeng Sun, Jin-Jian Hu, Chunyu Zhao, Youqi Tao, Xing Zhang, Dan Li, Yan-Mei Li*, Cong Liu*
"Parkinson's disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM"
Proc Natl Acad Sci USA, 2020, 117 (33): 20305-20315
DOI: 10.1073/pnas.1922741117

(6) Jun-Jun Wu, Lang Zhao, Hong-Guo Hu, Wen-Hao Li, Yan-Mei Li*
“Agonists and Inhibitors of the STING Pathway: Potential Agents for Immunotherapy”
Medicinal Research Reviews, 2020, 40(3), 1117-1141
DOI: 10.1002/med.21649

(7)Qian-Qian Li, Pu-Guang Chen, Zhi-Wen Hu, Yuan Cao, Liang-Xiao Chen, Yong-Xiang Chen, Yu-Fen Zhao, and Yan-Mei Li*
Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues
Chemical Science 2017, 8, 7675-7681
DOI: 10.1039/C7SC03217J

(8) Yu Shao†, Zhan-Yi Sun†, Yijie Wang, Bo-Dou Zhang, Dongsheng Liu*, Yan-Mei Li*
“Designable Immune Therapeutical Vaccine System Based on DNA Supramolecular Hydrogels”
ACS Applied Materials & Interfaces, 2018, 10, 9310-9314
DOI: 10.1021/acsami.8b00312

(9) Ting-Ting Chu, Na Gao, Qian-Qian Li, Pu-Guang Chen, Xi-Fei Yang, Yong-Xiang Chen*, Yu-Fen Zhao, and Yan-Mei LI*
Specific knockdown of endogenous tau protein by peptide-directed ubiquitin-proteasome degradation
Cell Chemical Biology 2016, 23, 453-461
DOI：10.1016/j.chembiol.2016.02.016

(10) Hui Cai, Zhan-Yi Sun, Mei-Sha Chen, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
“Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells”
Angewandte Chemie- International Edition 2014, 53(6), p1699-1703 (Hot Paper)

(11) Hui Cai, Mei-Sha Chen, Zhan-Yi Sun, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
“Self-Adjuvanting Synthetic Antitumor Vaccines from MUC1 Glycopeptides Conjugated to T-Cell Epitopes from Tetanus Toxoid”
Angewandte Chemie- International Edition 2013, 52, p6106-6110

(12) Zhi-Hua Huang, Lei Shi, Jing-Wen Ma, Zhan-Yi Sun, Hui Cai, Yong-Xiang Chen, Yu-Fen Zhao, and Yan-Mei Li*
“A totally synthetic, self-assembling, adjuvant-free MUC1 glycopeptide vaccine for cancer therapy”
Journal of the American Chemical Society 2012, 134(21), 8730-8733

(13)Hui Cai#, Zhi-Hua Huang#, Lei Shi, Zhan-Yi Sun, Yu-Fen Zhao, Horst Kunz* and Yan-Mei Li*
“Variation of the Glycosylation Pattern in MUC1 Glycopeptide BSA Vaccines and its Influence on the Immune Response”
Angewandte Chemie- International Edition 2012, 51(7), 1719-1723
DOI: 10.1002/anie.201106396

(14) Anton Kaiser, Nikola Gaidzik, Torsten Becker, Clara Menge, Kai Groh, Hui Cai, Yan-Mei Li, Bastian Gerlitzki, Edgar Schmitt and Horst Kunz*
“Fully Synthetic Vaccines Consisting of Tumor-Associated MUC1 Glycopeptides and a Lipopeptide Ligand of the Toll-like Receptor 2”
Angewandte Chemie- International Edition 2010, 49, pp3688-3692
DOI: 10.1002/anie.201000462

(15) Jin-Tang Du, Yan-Mei LI*, Wei Wei, Guo-Shi Wu, Yu-Fen Zhao, Kenji Kanazawa, Tadashi Nemoto, Hiroshi Nakanishi
“Low Barrier Hydrogen Bond Between Phosphate and the Amide Group in Phosphopeptide”
Journal of the American Chemical Society 127, 2005, p16350-16351
DOI: 10.1021/ja054568p

2021年

Zhang S#, Liu Y Q#, Jia C#, Lim Y J#, Feng G#, Xu E, Long H, Kimura Y, Tao Y, Zhao C, Wang C, Liu Z, Hu J J, Ma M R, Liu Z, Jiang L, Li D, Wang R, Dawson V L, Dawson T M*, Li Y M*, Mao X*, Liu C*.
“Mechanistic basis for receptor-mediated pathological alpha-synuclein fibril cell-to-cell transmission in Parkinson's disease.”
Proc Natl Acad Sci U S A 2021, 118 (26).

Li W H, Wu J J, Wu L, Zhang B D, Hu H G, Zhao L, Li Z B, Yu X F*, Li Y M*.
“Black phosphorous nanosheet: A novel immune-potentiating nanoadjuvant for near-infrared-improved immunotherapy.”
Biomaterials 2021, 273, 120788.

Liang C Q, Wang L, Luo Y Y, Li Q Q, Li Y M*.
“Capturing protein droplets: label-free visualization and detection of protein liquid-liquid phase separation with an aggregation-induced emission fluorogen.”
Chem Commun (Camb) 2021, 57 (31), 3805-3808.

Wu J J, Zhao L, Han B B, Hu H G, Zhang B D, Li W H, Chen Y X, Li Y M*.
“A novel STING agonist for cancer immunotherapy and a SARS-CoV-2 vaccine adjuvant.”
Chem Commun (Camb) 2021, 57 (4), 504-507.

Liu Y Q#, Mao Y Y#, Xu E Q, Jia H M, Zhang S, Dawson V L, Dawson T M, Li Y M*, Zheng Z*, He W W*, Mao X B*.
“Nanozyme scavenging ROS for prevention of pathologic α-synuclein transmission in Parkinson’s disease.”
Nano Today 2021, 36, 101027.

Liang C Q, Li Y M*.
“Peptides for disrupting and degrading amyloids.”
Curr Opin Chem Biol. 2021, 64, 124-130.

Zhang M Q, He P Y, Li Y M*.
“Contemporary Approaches to α,β-Dehydroamino Acid Chemical Modifications.”
Chem. Res. Chinese Universities 2021, 37(5), 1044-1054

Luo Y Y, Wu J J, Li Y M*.
“Regulation of Liquid-Liquid Phase Separation with Focus on Post-Translational Modifications.”
Chem Commun (Camb) 2021, 57, 13275-13287.

Zhao L, Wu, JJ and Li Y M*.
“Poly(ADP-ribose): the structure and the synthesis.”
Arkivoc 2021, iv, 65-88.

2020年

Li,Wen-Hao; Li, Yan-Mei*
“Chemical Strategies to Boost Cancer Vaccines.”
Chem. Rev. 2020, 120, 11420-11478.

Zhao, Kun#; Lim, Yeh-Jun#; Liu, Zhenying#; Long, Houfang; Sun, Yunpeng; Hu, Jin-Jian; Zhao, Chunyu; Tao, Youqi; Zhang, Xing; Li, Dan; Li, Yan-Mei*; Liu, Cong*
“Parkinson’s disease-related phosphorylation at Tyr39 rearranges α-synuclein amyloid fibril structure revealed by cryo-EM.”
Proc. Natl. Acad. Sci. USA 2020, 117, 20305–20315.

He, Pei-Yang; Chen, Huai; Hu, Hong-Guo; Hu, Jin-Jian, Lim, Yeh-Jun; Li, Yan-Mei*
“Late-stage peptide and protein modifications through phospha-Michael addition reaction.”
Chem. Commun. 2020, 56, 12632-12635.

Han, Bei-Bei#; Pan, Yu-Chen#; Li, Yan-Mei; Guo, Dong-Sheng*; Chen, Yong-Xiang*
“A host-guest ATP responsive strategy for intracellular delivery of phosphopeptides.”
Chem.Commun. 2020,56,5512-5515.

Li, Qian-Qian; Liu, Yu-Qing; Luo, Yun-Yi; Chu, Ting-Ting; Gao, Na; Chen, Pu-Guang; Chen, Yong-Xiang; Li, Yan-Mei*
“Uncovering the pathological functions of Ser404 phosphorylation by semisynthesis of a phosphorylated TDP-43 prion-like domain.”
Chem.Commun. 2020,56,5370-5373.

Li, Gao; Yang, Wu-Yue; Li, Wen-Hao; Luo, Yun-Yi; Lim, Yeh-Jun; Li, Yang; Paul, Ashim; Segal, Daniel; Hong, Liu; Li, Yan-Mei*
“Rational Design of a Cocktail of Inhibitors against A beta Aggregation.”
Chem. Eur. J, 2020, 26, 3499-3503.

Chen, Pu-Guang; Hu, Hong-Guo; Sun, Zhan-Yi; Li, Qian-Qian; Zhang, Bo-Dou; Wu, Jun-Jun; Li, Wen-Hao; Zhao, Yu-Fen; Chen, Yong-Xiang; Li, Yan-Mei*
“Fully Synthetic Invariant NKT Cell-Dependent Self-Adjuvanting Antitumor Vaccines Eliciting Potent Immune Response in Mice.”
Mol. Pharm. 2020, 17, 2, 417-425

Wu, Jun-Jun; Zhao, Lang; Hu, Hong-Guo; Li, Wen-Hao; Li, Yan-Mei*
“Agonists and inhibitors of the STING pathway: Potential agents for immunotherapy.”
Med. Res. Rev. 2020, 40, 1117-1141.

Liu, Chengcheng; Zhang, Wanlin; Zhao, Yang; Lin, Changxu; Zhou, Kang; Li, Yanmei; Li, Guangtao*
“Urea-Functionalized Poly(ionic liquid) Photonic Spheres for Visual Identification of Explosives with a Smartphone.”
ACS Appl. Mater. Inter. 2019, 11, 21078-21085.

Paul, Ashim; Li, Wen-Hao; Viswanathan, Guru KrishnaKumar; Arad, Elad; Mohapatra, Satabdee; Li, Gao; Jelinek, Raz; Gazit, Ehud; Li, Yan-Mei; Segal, Daniel*
“Tryptophan-glucosamine conjugates modulate tau-derived PHF6 aggregation at low concentrations.”
Chem. Commun. 2019, 55, 14621-14624

Paul, Ashim; Zhang, Bo-Dou; Mohapatra, Satabdee; Li, Gao; Li, Yan-Mei; Gazit, Ehud; Segal, Daniel*
“Novel Mannitol-Based Small Molecules for Inhibiting Aggregation of alpha-Synuclein Amyloids in Parkinson's Disease.”
Front. Mol. Biosci. 2019, 6, 16.

Gao, Na; Huang, Yun-Peng; Chu, Ting-Ting; Li, Qian-Qian; Zhou, Bing; Chen, Yong-Xiang*; Zhao, Yu-Fen; Li, Yan-Mei*
“TDP-43 specific reduction induced by Di-hydrophobic tags conjugated peptides.”
Bioorg. Chem, 2019, 84, 254-259.

Duan, Hua-Zhen; Chen, Hong-Xue; Yu, Qing; Hu, Jun; Li, Yan-Mei; Chen, Yong-Xiang*
“Stereoselective synthesis of a phosphonate pThr mimetic via palladium-catalyzed gamma-C(sp(3))-H activation for peptide preparation.”
Org. Biomol. Chem. 2019, 17, 2099-2102.

Chen, Huai; Zhao, Yu-Fen; Chen, Yong-Xiang; Li, Yan-Mei*
“Exploring the Roles of Post-Translational Modifications in the Pathogenesis of Parkinson's Disease Using Synthetic and Semisynthetic Modified alpha-Synuclein.”
ACS. Chem. Neurosci., 2019, 10, 910-921.